Burden of Cardiometabolic Disorders among Subjects Undergoing Preventive Health Check-up: A Follow-up Study

J N Pande, Manpreet Kaur, Harshpal Singh Sachdev


Objective: To study the incidence of hypertension (HTN), diabetes mellitus and coronary artery disease (CAD) in a cohort of adult subjects.

Methods: A total 2159 participants (mean age: 48.6±11.6 years; 1342 males and 817 females) who attended the hospital for a comprehensive health check up were recruited and followed-up as a cohort for a mean period of 3.5 years. Their baseline and follow-up evaluation included clinical examination, biochemical investigations and cardiac check-up.

Results: At baseline, 64% participants were overweight or obese, 44.3% had HTN (grade I or above), 16.7% had diabetes mellitus with additional 29.3% having impaired fasting glucose or glucose intolerance, and 46.6% had metabolic syndrome. The prevalence of CAD at baseline was 6% in males and 3% in females. The incidence (per 1000 person-years of follow-up) of HTN, diabetes mellitus and CAD was 72.2, 26.3 and 12.2, respectively.

Conclusion: The burden of cardiometabolic disorders and their risk factors is high in India. Urgent remedial public health preventive measures are required to curtail the emerging epidemic of cardiometabolic disorders.


Hypertension, diabetes mellitus, coronary artery disease, cardiometabolic syndrome.

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