Clinical Epidemiological Study of Oral Pre-cancer and Cancer in a Tertiary/Referral Hospital

Sadaksharam Jayachandran

Abstract


Aim: To study the prevalence of oral cancer in patients reported to the Department of Oral Medicine and Radiology, Tamil Nadu Government Dental College and Hospital.

Materials and Methods: After selecting the patients with the clinical criteria the history of the habits, duration in months and frequency per day, duration of the symptoms, oral mucosal site involvement, lymph node involvement, associated with lesions were recorded in a structured proforma. Incisional biopsy under Local anaesthesia and histological examination was performed. The results obtained were analysed statistically.

Results: 200 patients were diagnosed with oral cancer, 49% were male and 51% were females. In that 51(25%) were associated with premalignant lesions, 94 had only one habit, 74 had a combination of habits, 40% were histopathologically moderately differentiated followed by 33% poorly differentiated and 27% well differentiated. And patients with stage III (31%) and IV (43%) were reported predominantly than stage I (12%) and II (14%).

Conclusion: Early diagnosis and intervention prevent the progression of oral cancer.

Keywords : Tobacco, awareness, oral cancer, epidemiology.

 


Keywords


Tobacco, awareness, oral cancer, epidemiology.

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References


Warnakulasuriya S (2009). Global e p i d e m i o l o g y o f o r a l a n d oropharyngeal cancer. Oral Oncol 45(4):309-316.

Mehrotra R, Pandya S, Chaudhary AK, Kumar M, Singh M (2008). Prevalence of oral pre-malignant and malignant lesions at a tertiary level hospital in Allahabad, India. Asian Pac J Cancer Prev 9(2):263- 265.

Sheikh S, D'souza J (2012). A case of well-differentiated squamous cell carcinoma in an extraction socket. J Indian Soc Periodontol 16:602-605.

La Vecchia C, Tavani A, Franceschi S, Levi F, Corrao G, Negri E (1997). Epidemiology and prevention of oral cancer. Oral Oncol 33 : 302–312.

Clinical Epidemiological study of Oral pre-cancer and cancer in a Tertiary/Referral Hospital

Blot WJ, McLaughlin JK, Winn DM (1988). Smoking and drinking in relation to oral and pharyngeal cancer. Cancer Res 48: 3282–3287.

Ko YC, Huang YL, Lee CH, Chen MJ, Lin LM, Tsai CC (1995). Betel quid chewing, cigarette smoking and alcohol consumption related to oral cancer in Taiwan. J Oral Pathol Med 24(10):450-453.

Shirani S, Kargahi N, Razavi SM, Homayoni S (2014). Epithelial Dysplasia in Oral Cavity. IJMS 39(5):406-417.

Glick M, Feagans WM. Burkets Oral Medicine. 12th edition. USA S h e l t o n . P e o p l e s M e d i c a l Publishing House, 2015.

Neville BW, Day TA (2002). Oral cancer and precancerous lesions. CA Cancer J Clin 52(4):195-215.

B u r u n g a l e S U , D u r g e P M , Burungale DS, Zambare MB (2014). Epidemiological Study of Premalignant and Malignant Lesions of the Oral Cavity. JAIR 2(9):519-523.

Khandekar SP, Bagdey PS, Tiwari RR (2006). Oral Cancer and Some Epidemiological Factors : A Hospital Based Study. Indian Journal of Community Medicine 31(3):157-159.

Singh MP, Misra S, Rathanaswamy SP, et al. (2015). Clinical profile and epidemiological factors of oral cancer patients from North India. Natl J Maxillofac Surg 6:21-24.

Petridou E, Zavras AI, Lefatzis D (2002). The role of diet and specific micronutrients in the etiology of oral carcinoma. Cancer 94 : 2981–2988.

Gabriel HE, Liu Z, Crott JW, et al. ( 2 0 0 6 ) . A c o m p a r i s o n o f c a r o t e n o i d s , r e t i n o i d s , a n d tocopherols in the serum and buccal mucosa of chronic cigarette smokers versus nonsmokers. Cancer Epidemiol Biomarkers Prev 15(5):993-999.

Rodrigo R. Oxidative stress and antioxidants: their role in human disease. Nova Science Publishers: New York; 2009.

Babu S, Bhat RV, Kumar PU, et al. (1996). A comparative clinico- p a t h o l o g i c a l s t u d y o f o r a l submucous fibrosis in habitual chewers of pan masala and betel quid. J Toxicol Clin Toxicol 34(3):317-322.

Shukla A (2014). Potentially Malignant Disorders of the Oral Cavity: A Clinical Study. Indian J Otolaryngol Head Neck Surg 66(1):79–85.

Zain RB, Ghazali N (2001). A review of epidemiological studies of oral cancer and precancer in Malaysia. Annal Dent Univ Malaya 8: 50-56.

Messadi DV, Wilder-Smith P, Wolinsky L (2009). Improving Oral Cancer Survival: The Role of Dental Providers. J Calif Dent Assoc

(11):789-798.

Chestnutt IG, Binnie V (1995). Smoking cessation counselling--a role for the dental profession? Br Dent J 179(11):411-415.


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